Getting REBYOTA®

Everything you need to know about how to get REBYOTA and what
you should expect during your administration experience.

REBYOTA Patient Portrayal
Flowers on a vine

When discussing administration, talk to your doctor about your location options

Doctor icon

REBYOTA administration 
in your doctor’s office

REBYOTA can be administered right in your doctor’s office once you’ve completed your course of antibiotics. After administration, there is a 15-minute wait period, after which you can go home.

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If you are unable to receive REBYOTA in your doctor’s office, you may benefit from the option of administration via home health in the comfort of your home.


Freda, REBYOTA clinical study patient

I just knew that if I had C. diff again, I wasn’t going to survive. But my C. diff didn’t come back after I had REBYOTA.

– Freda, Clinical Study Patient

Most common side effects may include stomach pain, 
diarrhea, bloating, gas, and nausea.1

Individual results may vary.

For more information, please talk to your doctor and see full Prescribing Information. 
Freda was compensated for her time.

Getting ready for administration with REBYOTA1

Before administration icon


No preparation is required

  • You should complete your antibiotic prescription 1 to 3 days before your REBYOTA administration appointment
  • No laxatives/bowel prep or fasting are required
During administration icon


Takes place within minutes

  • Anesthesia or colonoscopy are not necessary
  • The doctor or nurse will place you in the preferred position for the administration
  • You will be asked to remain in place for about 15 minutes to minimize any cramping that may occur
After administration icon


Follow your doctor’s instruction

 Talk to your doctor…

  • If you experience any side effects
  • Before taking antibiotics for any
reason for 8 weeks after
administration of REBYOTA

Most common side effects may include stomach pain, diarrhea, bloating, gas, and nausea.1 These side effects could occur during the first 2 weeks after administration.1 This may not mean your recurrent C. diff has come back.

Your REBYOTA Experience

Watch as a nurse shows you what to expect before, during, and after administration with REBYOTA.

REBYOTA is available by prescription only. Talk to your doctor to find out if REBYOTA is right for you.

Candace, RN, CCRP, was compensated for her time.

REBYOTA Administration Experience

Talking to your doctor about recurrent C. diff and potential therapy options

Create your own customized discussion guide

Answering these questions will help you prepare for a conversation about C. diff with your doctor. This information is completely confidential and will not be saved for other use.

REBYOTA administration FAQs

Here are answers to general questions regarding REBYOTA.

Before administration

During administration

After administration


Keep exploring REBYOTA


Learn how one dose of REBYOTA can keep C. diff from coming back.


Patient stories

Watch as REBYOTA patients talk about
their journeys.

Patient stories

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  1. REBYOTA. Prescribing Information. Parsippany, NJ: Ferring Pharmaceuticals Inc; 2022.

Please see Important Safety Information and full Prescribing Information


REBYOTA (fecal microbiota, live – jslm) is indicated for the prevention of recurrence of Clostridioides difficile (C. diff) infection in individuals 18 years of age and older, following antibiotic treatment for recurrent C. diff infection.
Limitation of Use
REBYOTA is not indicated for the treatment of C. diff infection.

Important Safety Information

  • You should not receive REBYOTA if you have a history of a severe allergic reaction (e.g., anaphylaxis) to REBYOTA or any of its components.
  • You should report to your doctor any infection you think you may have acquired after administration.
  • REBYOTA may contain food allergens.
  • Most common side effects may include stomach pain (8.9%), diarrhea (7.2%), bloating (3.9%), gas (3.3%), and nausea (3.3%).
  • REBYOTA has not been studied in patients below 18 years of age.
  • Clinical studies did not determine if adults 65 years of age and older responded differently than younger adults.

You are encouraged to report negative side effects of prescription drugs to FDA. Visit or call 1-800-332-1088.

Please click to see the full Prescribing Information.

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